Spotfire web player does not support compatibilty mode, and you may see blank pages when opening the spotfire library in your browser window.
To ensure that the Web Player site is not being displayed in "Compatibility View". This is how you edit the Web Player server:
On the Web Player Server:
1. Start Microsoft IIS Manager.
2. Click on the Web Player website.
3. Open up the HTTP response header settings.
4. Add a setting with name="X-UA-Compatible" and value="IE=edge" .
Note: If the compatibility mode is disabled from the Web Player Server-side no action from the clients using the Web Player is required, i.e., end users can continue using Internet Explorer with their standard configuration
Please note this is solution to one of the causes and you may need to add the site to trusted zones or allow scripting depending on your infrastructure settings.